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Provencher Inc linear combination of model spectra (lcmodel)
Linear Combination Of Model Spectra (Lcmodel), supplied by Provencher Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lcmodel+(linear+combination+of+model+spectra)/linear+combination+of+metabolite+basis+spectra++lcmodel++program/pm34061383-121-18-24
Average 90 stars, based on 1 article reviews
linear combination of model spectra (lcmodel) - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Hypoglutamatergic state is associated with reduced cerebral glucose metabolism in anti-NMDA receptor encephalitis: a case report
Article Snippet: For spectroscopic analysis, the well-established and investigator-independent LCModel (linear combination of model spectra) algorithm was used ( www.s-provencher.com/pages/lcmodel.shtml ) [ , ].

Article Title: Prefrontal Glx and GABA concentrations and impulsivity in cigarette smokers and smoking polysubstance users.
Article Snippet: The even and the J-difference (odd-even) acquisitions were analyzed using LCModel (Linear Combination of Model spectra; Provencher, 1993).

Article Title: Metabolic effects of VO(dmpp)2– anex vivo1H-HRMAS NMR study to unveil its pharmacological properties
Article Snippet: The pharmacological action of the V(IV) compound VO(dmpp)2 was previously evaluated in vivo using obese pre-diabetic Zucker rats treated with this compound for four weeks.. Besides the promising results regarding biological parameters indicative of insulin-mimetism, a specific biological activity in mitigating impaired lipid metabolism was observed.. This work aims at complementing and reinforcing data formerly attained and it represents an attempt to unveil the effect of this compound at the molecular level, particularly on the metabolic profile of different organs.

Article Title: ARALAR/AGC1 deficiency, a neurodevelopmental disorder with severe impairment of neuronal mitochondrial respiration, does not produce a primary increase in brain lactate.
Article Snippet: Metabolite concentrations were calculated using the program LCModel (Linear Combination of Model Spectra; Provencher et al., 1993), which employs a constrained non-linear fitting algorithm that minimizes the differences between the linear combination of model spectra and the experimental spectrum.

Article Title: Non-invasive in vivo measurements of metabolic alterations in the type 2 diabetic brain by 1 H magnetic resonance spectroscopy.
Article Snippet: This article is part of the special issue “Energetics and cognition in aging brain: Impact of substrates and microbiome”.. Abbreviations: CSI, chemical shift imaging; GABA, γ-aminobutyric acid; MR, magnetic resonance; MRI, MR imaging; MRS, MR spectroscopy; NAA, N-acetylaspartate; NAAG, N-acetylaspartylglutamate; RF, radiofrequency; ROI, region of interest; T2D, type 2 diabetes; TE, echo time; TR, repetition time; VOI, volume of interest.. 1Hoglund Biomedical Imaging Center, University of Kansas Medical Center (KUMC), Kansas City, Kansas, USA 2Department of Neurology, KUMC, Kansas City, Kansas, USA 3Department of Radiology, KUMC, Kansas City, Kansas, USA 4Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA 5NeuroNetwork for Emerging Therapies, University of Michigan, Ann Arbor, Michigan, USA 6Department of Biomedical Sciences, University of North Dakota, Grand Forks, North Dakota, USA 7Department of Medicine, KUMC, Kansas City, Kansas, USA

Article Title: Effect of high‐intensity interval training on hippocampal metabolism in older adolescents
Article Snippet: MRS data from the hippocampal voxels were analyzed using an automated linear combination of model spectra (LCModel) with a custom‐made basis set for the LASER sequence at TE of 40 ms and 3 T (Provencher, ).

Software:

Article Title: Integrative Magnetic Resonance Imaging and Metabolomic Characterization of a Glioblastoma Rat Model
Article Snippet: .. Two spectra per sample were acquired, one with a total TE of 36 ms and another of 144 ms. Then, the detectable metabolites were quantified using the LCModel package (Linear Combination of Model Spectra, http://s-provencher.com/lcmodel.shtml ), a prior knowledge spectral fit software. ..

Article Title: Intramyocellular lipid accumulation after sprint interval and moderate‐intensity continuous training in healthy and diabetic subjects
Article Snippet: .. Data were analyzed using the linear combination of model spectra software package (LCModel) version 6.3‐0C (Provencher ) (Fig. ). ..



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